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Ongoing Regional Projects

1.
Outcomes Following Distal Femoral Replacement for Periprosthetic Distal Femur Fractures in the East of England 

Primary Aims
1. To determine the 30-day, 90-day, 1-year, 5-year and 10-year all-cause mortality following DFR for periprosthetic distal femur fractures across the NHS orthopaedic units in the East of England.
2. To evaluate inter-hospital variation in 1-year mortality across contributing centres and identify centre-level factors associated with outcome.
3. To assess return to baseline mobility following DFR, measured by the Parker Mobility Score (PMS), compared to pre-injury baseline — applicable to all patients regardless of cognitive status.

 

Secondary Aims
4. To identify patient-level risk factors independently associated with 30-day, 90-day and 1-year morbidity and mortality.
5. To characterise the early and late complication profile of DFR in this region: PJI rates, aseptic loosening, mechanical failure, revision surgery, and wound complications.
6. To record time from injury to surgery and evaluate its association with complication rate and mortality.

To get involved, contact: sai.grandhi@nhs.net

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